Note: Fixation guidelines of 6 to 48 hours are mandated by College of American Pathologists (CAP) and American Society of Clinical Oncology (ASCO). HER2/neu by Immunohistochemistry (IHC) will not be performed on specimen that is fixed outside required timeline. Those cases will be sent to Mayo Medical Laboratories for HER-2/neu Amplification Associated with Breast Cancer, FISH.
Unfavorable >2.4%
Equivocal >1.5-<2.4
Assay results:
Staining Intensity Average
Note: Her2/neu scoring has been validated in accordance with CAP and ASCO guidelines.
This test is performed using the FDA approved DAKO testing kit in strict accordance to the manufacturer’s instructions.
Scoring is performed on the FDA approved ACIS III Imager.
CPT Code:
88361