Lavender top tube
1 mL plasma
0.60 mL plasma
Collect specimen in a lavender top tube (EDTA). Centrifuge, aliquot plasma into a plastic vial, and freeze within 2 hour. Do not refrigerate the sample.
Collect specimen in a lavender top tube (EDTA). Transport specimen at room temperature. Centrifuge, aliquot plasma into a plastic vial, and freeze within 2 hour.
Tuesday, Friday
8 hours
Chemiluminescence
Upright: <= 40 years, 4.0 - 44.0 pg/mL; > 40 years, 4.0 - 60 pg/mL Supine (more than 30 minutes): <= 40 years; 3.0 - 30 pg/mL; > 40 years, 3.0 - 42.0 pg/mL. Contact the MLabs Client Services Center for interpretation by the Hypertension Unit (936-4790).
Evaluate the role of renin in the differential diagnosis of hypertension.
When screening for primary hyperaldosteronism, both renin and aldosterone are best interpreted together. 1) If plasma renin mass is less than 8 pg/mL and: · aldosterone of less than 10 ng/dL: Unlikely primary aldosteronism · aldosterone of 10 to 20 ng/dL: Possible primary aldosteronism · aldosterone of greater than 20 ng/dL: Suggestive of primary aldosteronism 2) If plasma renin mass is greater than or equal to 8 pg/mL and: · the ratio of aldosterone to plasma renin mass is greater than 2.6 (ng/dL:pg/mL), findings are suggestive of primary aldosteronism Multiple factors including medications, sodium status, and other causes may influence these values and could potentially lead to false-positive or false-negative results; these factors should be considered in interpretation as noted in Endocrine Society guidelines [Funder JW et al. J Clin Endocrinol Metab. 2016, 101(5):1889-1916]. Screening BPA Interpretation Guide
35570-1
84244
KA016
Specimen not drawn in lavender top tube, specimen not frozen, specimen refrigerated, clotted sample.